精神活性药物
The Library of Psychoactive Drugs is a curated collection of compounds known for their ability to have a significant impact on human brain function. These substances affect a person's perception, mood, consciousness, or behavior. The library encompasses a range of psychoactive agents, including sedatives, hypnotics, antipsychotics, and antidepressants. This data can serve as a valuable resource in research on the neurological and behavioral effects of psychoactive compounds.
The Library of Psychoactive Drugs contains 132 molecules. The mechanisms of
action and their effects on the CNS are known for all presented compounds.
Related terms: Catechol-O-methyltransferase, GPСR, 5-HT2A receptor, antipsychotics, neurotrophic receptor tyrosine kinase, GABA, antidepressants, butyrylcholinesterase, TRPM6.
Highlights
Risperidone is a second-generation antipsychotic medication.
Granisetron is a serotonin 5-HT3 receptor antagonist.
Amoxapine is a tetracyclic antidepressant.
Sultopride is an atypical antipsychotic used for the treatment of schizophrenia.
Product Features
Psychoactive Drugs Library is a set of 132 molecules with sub-10 micromolar activity coefficient values for HTS/HCS programs.
The library comprises of psychoactive drugs, each with distinct mechanisms of action and effects on the CNS.
Calculated structural diversity of the collection: 0.86.
Comprehensive documentation with structures, trivial names, synonyms, activity coefficient values, types of action on target and references to original literature.
NMR and LCMS validated purity.
All the compounds are available in stock for hit follow-up.
The library is continuously updated.
Product Details
Format: 10 - 100 µL of 10 mM DMSO stock solutions; dry powders (1 mg);
Container: 384-well microplates;
Storage: - 18 °C;
Shipping: Dry ice.
Utility
High throughput screening (HTS);
High content screening (HCS);
Cherry picking.
